Last reviewed: February 2026

Upset Stomach
📊 20-40% Of adults affected
🍽️ After Eating Common timing
🔍 Often Functional No structural cause
Treatable Multiple approaches

📖 What is Indigestion?

Indigestion, medically known as dyspepsia, refers to discomfort or pain in the upper abdomen, typically occurring during or after eating. It is not a disease itself but a collection of symptoms that may indicate various underlying conditions - or no identifiable cause at all.

Common Symptoms

What Indigestion is NOT

While often confused, indigestion is distinct from:

📋 Types of Dyspepsia

Functional Dyspepsia

When no structural or biochemical cause is found despite investigation (60-70% of cases). Subdivided into:

Organic Dyspepsia

When a specific cause is identified:

🔬 Causes of Indigestion

Lifestyle & Dietary

Medical Conditions

ConditionAdditional Clues
Peptic ulcerPain may improve or worsen with food; history of NSAIDs
H. pylori gastritisChronic symptoms; testing confirms infection
GERDHeartburn, regurgitation, worse when lying down
Gallbladder diseaseRight upper abdomen pain, after fatty meals
GastroparesisNausea, vomiting, diabetes or post-surgical
Celiac diseaseBloating, diarrhea, weight loss
Chronic pancreatitisSevere pain, radiates to back, fatty stools

Medications That Cause Indigestion

🚨 When to See a Doctor

Alarm Symptoms - Seek Medical Care:
  • Unintentional weight loss
  • Difficulty swallowing (dysphagia)
  • Persistent vomiting
  • Vomiting blood or coffee-ground material
  • Black, tarry stools
  • Anemia or low blood counts
  • Abdominal mass or swelling
  • Jaundice (yellow skin/eyes)
  • New symptoms after age 55-60
  • Family history of GI cancer

These "alarm features" require prompt investigation, typically with upper endoscopy, to rule out serious conditions including cancer.

🔍 Diagnosis

Initial Assessment

Testing

Functional Dyspepsia Criteria

Rome IV criteria require symptoms for at least 3 months with onset at least 6 months before diagnosis, AND no structural disease found on evaluation.

💊 Treatment

Step 1: Lifestyle Modifications

Step 2: Acid Suppression

Step 3: H. pylori Eradication

If H. pylori positive, treatment involves triple or quadruple therapy:

For Functional Dyspepsia

🏠 Home Remedies

Quick Relief

Traditional Remedies

Digestive Tea Recipe: Boil 1/2 teaspoon each of cumin, coriander, and fennel seeds in 2 cups of water for 5 minutes. Strain and sip after meals.

🥗 Diet for Indigestion

Foods to Choose

Foods to Limit

Eating Habits

Frequently Asked Questions

Is indigestion the same as heartburn?

No, though they often occur together. Indigestion (dyspepsia) refers to upper abdominal discomfort - pain, fullness, bloating. Heartburn is a burning sensation behind the breastbone caused by acid reflux. They have different causes and may require different treatments.

Can indigestion be a sign of something serious?

Usually indigestion is not serious. However, if you have alarm symptoms (weight loss, difficulty swallowing, vomiting blood, black stools), or if you are over 55 with new symptoms, see a doctor. Rarely, indigestion symptoms can signal conditions like stomach cancer or ulcers.

Why do I get indigestion at night?

Nighttime indigestion often relates to eating too close to bedtime, lying down too soon after eating, or having large evening meals. Eating earlier, smaller dinners and staying upright for 2-3 hours after eating can help. Sleeping with the head elevated may also provide relief.

How long should I try lifestyle changes before seeing a doctor?

If you have no alarm symptoms, try lifestyle changes for 2-4 weeks. If symptoms persist, see a doctor for evaluation and possibly a trial of acid-suppressing medication. Persistent or worsening symptoms should always be evaluated.